Viral Diseases of the Respiratory Tract

Question Answer
Adenoids (blank)
Adenoviruses naked, dsDNA-containing viruses for which there are at least 50 stereotypes–immunity lifeong and type specific–originally isolated from adenoids–latent in tissue for life–colds severe with fever–
Antigenic drift mutation change of hemagglutininand neuraminidase
Antigenic shift complete hemagglutinin gene change
Chicken pox varicella virus–one of the most highly contagious diseases known–rash lasts 2-3 wks–itching–
Common cold (blank)
Congenital rubella syndrome when a pregnant woman passes rubella virus to fetus during first trimester–any organs can be affected–eyes, brain, abdominal and thoracic organs, bone, etc.
Guillain-Barre syndrome risk that occurs rarely–1 in every million doses of flu vaccine– sx–neural damage, paralysis, and coma
Hemagglutinin viral protein that attaches virus to ciliated epithelial cells in throat so virus can enter and kill cells–influenza virus
Influenza virus spreads from person to person in 2-3 days–fever, chills, headache, and muscle pains–cough develops and transmits virions–sx last 7-10 days–killed vaccine produced each year for expected antigenic types
Iron lungs large steel tanks–children condemned to live in–only machines available to provide a pressure change on chest to force breathing–poliovirus tx
Keratoconjunctivitis inflammation of the conjunctiva and the cornea of the eye
Koplik's spots reddish patches with white, salt crystal-like centers–first described by Dr. Henry Koplik–measles virus
Local epidemic both hemagglutinin and neuraminidase can change in small steps by mutation–happens on a yearly basis–influenza virus
Measles virus causes rubeola–7 day measles–most distinctive diagnostic sign is Koplik's spots–mild in most pts–highly contagious–vaccine developed in early 1960's
Mumps virus inflamation of the parotid gland (parotitis)–glandular orifice swells shut, fills with saliva, becomes tight and tender–chewing becomes painful–testes can become infected (orchitits) and sterility can occur–live attenuated vaccine developed in 1967
Neuraminidase surface viral protein that breaks down the protective mucous layer that lines the throat–influenza virux
Poliovirus tiny RNA virus that infects the alimentary canal–invades neurons in spinal column–causes poliomyelitis–transmitted in water or food-initial infection in adenoids/lymphatic tissue intestinal tract–sometimes spread via bloodstream to meninges-
Respiratory syncytial virus causes a serious infection of lower resp. tract in young children–spread in infant ward-tx ribavirin via resperator–infected seperated–induces syncytia
Reye's syndrome children under 17 given ASA get this
Rhinovirus cause 50% of common colds–people have 3-5 infections/year–no fever–spread via resp aerosols produced b coughing/sneezing–grow at cool temps of nose–do not invade via bloodstream–headache/sore throat/runny nose
Rubella virus causes 3 day measles/German measles–red rash lasts 3 days less pronounced than the measles rash–vaccine
Rubeola caused by measles virus
Sabin vacine live attenuated–kills polio virus
Salk vaccine killed vaccine–eliminated polio virus
Shingles caused by zoster virus–reccurent disease of chicken pox–painful neuralgia–lasts 3-5 weeks–comes from cranial nuerons–rash appears where that neuron enervates skin on one side of face or body–facial paralysis can result–pain meds needed
Syncytia caused by respiratory syncytial virus–causes infected cells to fuse together